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Diagnostic tests for COPD (chronic obstructive pulmonary disease)-OSAHS (obstructive sleep apnoea/hypopnoea syndrome) overlap syndrome

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Diagnostic tests for COPD (chronic obstructive pulmonary disease)-OSAHS (obstructive sleep apnoea/hypopnoea syndrome) overlap syndrome

Diagnosing ventilatory failure

  • measure arterial or arterialised capillary blood gas when the person with suspected COPD-OSAHS overlap syndrome is awake, to assess for ventilatory failure
  • do not delay treatment for acute ventilatory failure to carry out further investigations for COPD-OSAHS overlap syndrome.

Diagnosing OSAHS or nocturnal hypoventilation in people with suspected COPD-OSAHS overlap syndrome

  • offer respiratory polygraphy, either in hospital or at home, to diagnose OSAHS in people with suspected COPD–OSAHS overlap syndrome
  • consider adding transcutaneous carbon dioxide (CO2) monitoring during sleep to respiratory polygraphy to provide additional information to guide treatment
  • do not use oximetry alone to diagnose OSAHS or nocturnal hypoventilation in people with suspected COPD–OSAHS overlap syndrome

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