HRT - equivalence options for different doses of transdermal oestradiol

Last edited 04/2022 and last reviewed 04/2022

Equivalence options for different doses of transdermal oestradiol

  • Evorel (25/50/75/100)
  • Estradot patches (25/50/75/100)
  • Estraderm patches (25/50/75/100)
  • Femseven mono (50/75/100)
  • Progynova TS (50/100)
  • For a dose of 25 can use half a patch of 50.
  • For a dose of 75 can use 3/4 of a patch of 100

  • Alternatively, could switch to a gel preparation as Oestrogel or Sandrena or Lenzetto spray to take with current progestogen intake as above:
    • If taking Evorel 25: Oestrogel one measure a day would give an equivalent.
    • If taking Evorel 50: Oestrogel one measure twice a day would give an equivalent.
    • If taking Evorel 75: Oestrogel three measures a day (2am and 1pm or vice versa) would give an equivalent.
    • If taking Evorel 100: Oestrogel 4 measures a day (2am and 2pm) would give an equivalent.
    • Or Sandrena gel:
      • If taking Evorel 25: 0.5mg Sandrena sachet a day would give an equivalent.
      • If taking Evorel 50: 1mg Sandrena sachet a day would give an equivalent.
      • Or Lenzetto three sprays (40mcgm) equivalent to two measures of Oestrogel or 50 microgram patch

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