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Epidemiology

Authoring team

  • Graves' disease is the commonest cause of hyperthyroidism
  • females affected more than males in the ratio 5:1
  • peak incidence from 30-50 years of age
  • may affect 2 to 5% of all females at some time
  • association with HLA B8 and HLA DR3 in Caucasians
  • there is some evidence that significant life events, for example, divorce or bereavement, may precipitate the development of Graves' disease
  • there is an association with smoking

Reference

  1. Wémeau JL et al. Graves' disease: Introduction, epidemiology, endogenous and environmental pathogenic factors. Ann Endocrinol (Paris). 2018 Dec;79(6):599-607

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