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Anticholinergics in asthma

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Vagal innervation provides tonic bronchoconstriction which is mediated by acetyl choline.

Cholinergic reflex bronchoconstriction may be triggered by:

  • irritants
  • cold
  • emotion

Anticholinergics are effective in preventing these pathways of bronchoconstriction. Atropine has been used but less soluble quaternary compounds, such as ipratropium bromide, result in fewer side-effects.


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