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Clinical case definition of AIDS in Africa

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In the absence of known causes of immunosuppression, e.g. cancer or malnutrition, AIDS in an adult is defined by the existence of at least two major signs with at least one minor sign. In addition generalised Kaposi's sarcoma or cryptococcal meningitis is sufficient for the diagnosis of AIDS.

Major signs:

  • greater than 10% loss in body weight
  • chronic diarrhoea for more than 1 month
  • prolonged intermittent or constant fever for more than 1 month

Minor signs:

  • persistent cough for more than 1 month
  • generalised pruritic dermatitis
  • recurrent Herpes zoster
  • oropharyngeal candidosis
  • chronic progressive and disseminated herpes simplex infection
  • generalised lymphadenopathy

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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