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Complications

Authoring team

Complications due to reduction in normal immunoglobulins:

  • recurrent infections

Complications due to the paraprotein:

  • renal failure
  • Fanconi's syndrome
  • amyloidosis
  • bleeding disorders due to coating of normal platelets with paraprotein

Complications of skeletal damage:

  • pathological fractures especially of the spine and sternum
  • hypercalcaemia of malignancy

Reference

  1. NICE. Myeloma: diagnosis and management. NICE guideline NG35. Published february 2016, last updated October 2018.

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