Complications
- septicaemia / pyaemia
- septic arthritis
- direct spread of infection
- deformity or alteration in growth rate due to damage to the growth plate
- amyloidosis
- squamous carcinoma of the skin lining the sinus (Marjolin's ulcer)
Note - in adults, the recurrence rate of chronic osteomyelitis is about 30% at 12 months, but in cases involving P. aeruginosa, the recurrence rate may be as high as 50%. Cases involving prosthetic devices are more difficult to treat, causing increased morbidity due to the need for more surgical procedures and extended antibiotic courses required for treatment.
Reference
- Calhoun JH, Manring MM. Adult osteomyelitis. Infect Dis Clin North Am. 2005 Dec;19(4):765-86
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