Mebendazole and albendazole re not recommended in children aged under 2 years. In this age group piperazine provides a useful alternative in the treatment of threadworm and roundworm infections (1).
Piperazine is available as an elixir and as a combination powder with senna which can be stirred into milk or water. Piperazine is thought to result in flaccid paralysis of susceptible worms, which are then rapidly evacuated from the gastrointestinal tract when using preparations containing senna.
Indications:
Cautions:
Contra-indications include:
Side-effects include:
Routes of administration:
Reference:
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