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Aetiology

Authoring team

The common causes of malabsorption in the UK are:

  • coeliac disease
  • lactose intolerance
  • chronic pancreatitis
  • small bowel resection
  • small bowel bacterial overgrowth
  • giardiasis

Tropical sprue is the most common cause worldwide.

Causes of malabsorption can be classified as:

  • lipolytic phase defects
  • micellar phase defects
  • mucosal defects
  • delivery phase defects
  • isolated brush border enzyme / transport protein defects
  • systemic disease

Reference

  1. Keller J, Layer P. The Pathophysiology of Malabsorption. Viszeralmedizin. 2014 Jun;30(3):150-4.

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