Chemotherapeutic drug administration
Normally the drugs are given intravenously.
Normally single chemotherapy is effective with combinations of 2 to 4 drugs being given in pulses. The pulsatile nature of the administration is more effective against tumours, causing less immunosuppression and myelosuppression
Combinations of drugs are selected based on:
- known single agent activity
- dissimilar toxic effects
- potentiation
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