This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Menetrier's disease

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Menetrier's disease is a disease of the stomach characterised by giant hypertrophy of the mucosa of the gastric fundus with cystic changes in the crypts; the antrum is spared. It is associated with protein loss - sometimes to the point of peripheral oedema. It is treated by partial gastrectomy, although the subsequent likelihood of malnutrition due to surgery must be weighed against the present nutritional deficit.

It may predispose to malignancy - Scharschmidt found that stomach carcinoma developed in 10% of cases (1).

The condition should be distinguished from hyper-rugosity of the gastric mucosa in which there is no protein loss and which may be associated with the Zollinger-Ellison syndrome.

Reference:

  • 1) Scharschmidt, B. (1977) The natural history of hypertrophic gastropathy (Menetrier's disease). A review based upon 120 cases. Am. J. Med. 63:644.

Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.