Richard Cabot described Cabot ring in the blood smears of anaemic patients as ring-shaped structures. The physiological mechanism of Cabot ring is unclear, it is reported to involve arginine-rich histones and non-haemoglobin iron.
It is also seen in severe haemolytic anaemias and pernicious anaemia, lead poisoning, homozygous thalassemia, and splenectomy.
Reference
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