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Meconium ileus

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Meconium ileus is a cause of neonatal intestinal obstruction caused by inspissated meconium. It is a neonatal manifestation in up to 20% of infants with cystic fibrosis.

The inspissated meconium obstructs the small intestine at the level of the terminal ileum. If left untreated, the prognosis is poor.

A related disorder known as meconium ileus equivalent may occur in later life.

Reference

  1. Sathe M, Houwen R. Meconium ileus in Cystic Fibrosis. J Cyst Fibros. 2017 Nov;16 Suppl 2:S32-S39

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