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Other therapies

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Less common approaches to treatment include:

high dose corticosteroids } all have substantial
cyclophosphamide } toxicity and should not be
cyclosporin A } used routinely
human haematopoietic growth factors - granulocyte colony stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GH-CSF) effectively increase granulocytes, with red cells and platelets unaffected. Response requires at least a low level of ongoing haematopoiesis. Growth factors should not be used as the sole means of therapy in severe aplastic anaemia unless there is a rare primary growth factor deficiency.

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