clinical features

Last reviewed 08/2021

  • usually occurs in adults
    • idiopathic cases (the vast majority) typically affect adults between 30 and 50 years old (males more than females)

  • presentation:
    • proteinuria or nephrotic syndrome (80%)
    • hypertension (10-50%) seems to depend on the amount of renal damage
    • haematuria is rare

  • features of underlying cause e.g. systemic lupus erythematosus, hepatitis B infection, drug history (e.g. penicillamine, gold)

  • 70% of patients with idiopathic membranous nephropathy have a complete or partial spontaneous remission of nephrotic syndrome with stabilisation of renal function