This site is intended for healthcare professionals

CPD
CPD
Pro
Pro
Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Go to /pro/cpd-dashboard page

This page is worth 0.05 CPD credits. CPD dashboard

Go to /account/subscription-details page

This page is worth 0.05 CPD credits. Upgrade to Pro

Tizanidine in the treatment of spasticity

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

  • related to clonidine

  • it is thought to work via the stimulation of pre-synaptic alpha-2 adrenoreceptors, and the enhancement of noradrenergic inhibition of polysynaptic reflexes

  • there is evidence that tizanidine reduces the frequency of muscle spasms and reduces spastic muscle tone - however there was no diminition in muscle strength (1)

  • the most common side effects of tizanidine are dry mouth, drowsiness and subjective muscle weakness - however muscle weakness (objective and subjective) is less common than with treatment with diazepam or baclofen

Reference:

  • 1) Wallace JD (1994). Summary of combined analysis of controlled clinical trials with tizanidine. Neurology 44 (Suppl 9), s60-9.

Related pages

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.