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Cranial irradiation

Authoring team

Cranial irradiation is used in high dose for intracranial malignancy alone, or in conjunction with surgery and chemotherapy.

It is effective in treating sanctuary sites of leukaemia in the brain.

Side effects include:

  • reduced IQ - degradation of short term memory, arithmetic and attention
  • hypothalamic pituitary damage - including hypothyroidism, growth hormone deficiency and precocious puberty

These adverse effects are worse:

  • with higher doses and increased frequency of therapy
  • with young children

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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