This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Cautions and contraindications

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Cardiac glycosides should be used with caution in:

  • recent myocardial infarction
  • constrictive pericarditis - for a similar reason
  • hypothyroidism - decreased efficacy and increased risk of toxicity
  • chronic cor pulmonale - decreased efficacy and increased risk of toxicity
  • elderly - smaller doses needed
  • renal impairment - smaller doses needed
  • avoid hypokalaemia
  • avoid rapid intravenous administration

Contraindications include:

  • arrythmias associated with accessory conduction pathways (e.g. Wolff-Parkinson-White syndrome) - these drugs should not be used to treat these sorts of arrythmia because they will impair conduction through the normal conducting pathway without affecting the accessory pathways
  • intermittent complete heart block, second degree AV block
  • left ventricular outflow obstruction (e.g. HOCM, aortic stenosis) increase force of contraction against an obstruction - occasionally digoxin may be used if concomitant atrial fibrillation and heart failure - consult expert advice on management in this situation

Note that digoxin interacts significantly with many drugs.

The summary of product characteristics should be consulted before prescribing this drug.


Related pages

Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.