This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Non steroidal anti-inflammatory drugs

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Non-steroidal anti-inflammatory drugs (NSAIDS) act to reduce inflammation and pain by interupting the synthesis of prostaglandins.

NSAIDS inhibit the enzyme cyclo-oxygenase (COX).

As single dose for acute pain there is probably no advantage of NSAIDs over paracetamol; however with chronic inflammatory conditions regular NSAID therapy offers prolonged pain relief with a useful anti-inflammatory action.

Despite their efficacy, NSAIDs are limited by their gastrointestinal side-effects, particularly gastric ulceration.

NICE suggest that a clinician should

  • co-prescribe a PPI for people over 45



Related pages

Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page