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Gastrointestinal manifestations

Authoring team

Gastrointestinal manifestations include:

  • pancreatic insufficiency leading to malabsorption and failure to thrive
  • gynaecomastia and other signs of chronic liver disease such as hepatosplenomegaly
  • liver cirrhosis, portal hypertension, hypersplenism - which may develop because of intrahepatic bile duct obstruction caused by abnormal inspissated bile
  • distal ileus obstruction syndrome - meconium ileus equivalent
  • rectal prolapse (in children) - due to bulky stools
  • biliary stricture
  • gallstones, cholecystitis
  • intussusception
  • acute or chronic pancreatitis.

 

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