Drugs with significant first pass hepatic metabolism
The following drugs have significant first pass hepatic metabolism:
- chlorpromazine
- aspirin
- oestrogens
- enalapril
- prazepam
- amitriptyline
- nortriptyline
- imipramine
- pentazocine
- pethidine
- chlormethiazole
- isosorbide dinitrate
- glyceryl trinitrate
- lignocaine
- oxprenolol
- propranolol
- labetolol
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