Laboratory features
Micrangiopathic haemolytic anaemia is characterised by:
- fragmented red blood cells - schistocytes, helmet cells, triangle forms - in peripheral blood smear
- normocytic, normochromic
- Hb usually < 10 gm/dl
- marked reticulocytosis; occasionally, nucleated RBC's
- haemolysis - increased serum indirect bilirubin, LDH, and serum haemoglobin; absent haptoglobin
- negative Coomb's test
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