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Piperadine compounds produce less extrapyramidal side effects than other phenothiazines and so often used in elderly patients.
They may produce pigmentation of the retina in some patients and should not be given in large doses for long periods.
The CSM has advised that the use of thioridazine should be restricted to the second line treatment of schizophrenia in adults (1):
The summary of product characteristics should be consulted before prescribing this drug.