Aldactone (R)
Spironolactone is an aldosterone antagonist (also reduces the activity of the enzyme Na+K+ATPase in renal tubular cells (1)) used in the treatment of:
- oedema and ascites in liver cirrhosis
- malignant ascites
- nephrotic syndrome
- congestive heart failure
- primary aldosteronism
Contraindications include:
- hyperkalaemia
- severe renal impairment
- pregnancy and breast feeding
- Addison's disease
- porphyria
The summary of product characteristics must be consulted before prescribing this drug.
Related pages
Create an account to add page annotations
Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page