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Thrombolysis is the dissolution of a blood clot.
Thrombolysis occurs physiologically during haemostasis but accelerated thrombolysis is desirable in:
Thrombolytic therapy is routine in the management of peripheral arterial thrombosis and myocardial infarction. Thrombolysis in the treatment of stroke remains contraversial.
Studies have shown that thrombolysis in myocardial infarction is most beneficial when given within 90 min of the onset of symptoms, although a beneficial effects is seen if administration is delayed for up to 12 hr.
Depending on the local circumstances, optimal thrombolysis may require: