Systemic disorders causing pain in the hands and wrists

Systemic disorders causing pain in the hands and wrists often involve inflammation or nerve issues related to the body's overall condition. The primary causes are various forms of arthritis and metabolic diseases. Specific systemic disorders that can lead to pain in the hands and wrists include:

• Rheumatoid Arthritis
• Psoriatic Arthritis
• Gout
• Lupus (Systemic Lupus Erythematosus or SLE)
• Scleroderma (Systemic Sclerosis or SSc)
• Diabetes
• Hypothyroidism
• Sjögren's Syndrome
• Infections

Many of these conditions can also lead to secondary problems like carpal tunnel syndrome or tenosynovitis (inflammation of the tendon sheath), which directly cause pain in the hands and wrists.