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Interruption of lymphocyte migration

Authoring team

Accepted treatments which are thought to act at least in part by inhibiting the migration of lymphocytes into the CNS include:

  • corticosteroids
  • interferon beta

Experimental approaches include:

  • blocking monoclonal antibodies to:
    • VLA-4
    • ICAM-1
    • integrins

  • matrix metalloproteinase inhibitors

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