Guillain-Barre syndrome occurs sporadically at any age from early infancy.
It often follows viral infections:
The viral illness has usually run its course by the time the neurological symptoms appear, and there is no evidence for viral invasion of the nervous system. About 2.5% of cases occur in patients with autoimmune disorders, including systemic lupus erythematosus and rheumatoid arthritis.
Other associations include:
Reference:
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