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Lymphoma of the small intestine

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Primary lymphoma of the small intestine may be one of two types. The Western type is a focal tumour of lymphoid tissue, 20% of which are multiple. The Mediterranean type is a form of immunoproliferative disease characterized by a proliferation of lymphoid tissue along the whole length of the small intestine. It is associated with alpha-chain disease, in which there is a proliferation of plasma cells in the lamina propria of the small intestine, with a pre-malignant potential.

The small intestine may be involved in secondary lymphoma, but a primary form is more likely in the absence of lymphomatosis, lymphadenopathy or hepatosplenomegaly.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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