This site is intended for healthcare professionals
Last reviewed dd mmm yyyy. Last edited dd mmm yyyy
This is characterised by a primary decrease in serum bicarbonate and a slight decrease in paCO2. Serum pH may be reduced or normal.
Causes are distinguished on the basis of the anion gap. In acidosis with a normal anion gap, plasma chloride is increased in order to maintain electrical neutrality - hyperchloraemic acidosis.