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Metabolic acidosis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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This is characterised by a primary decrease in serum bicarbonate and a slight decrease in paCO2. Serum pH may be reduced or normal.

Causes are distinguished on the basis of the anion gap. In acidosis with a normal anion gap, plasma chloride is increased in order to maintain electrical neutrality - hyperchloraemic acidosis.

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