This groups compared radical mastectomy with quadrantectomy, axillary dissection and breast irradiation. Those patients with proven nodal metastases also received adjuvant chemotherapy. It was a prospective, randomised control trial.
The study group was 701 women with primary tumours less than 2cm in diameter and no clinically-palpable nodes.
The study followed both groups for 13 years. At this stage, survival was similar: 69% for mastectomy and 71% for conservative treatment. Also, local recurrence rates were similar.
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