This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Foreign body giant cell

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

A foreign body giant cell is a very large cell formed by the fusion of multiple macrophages, typically epitheloid cells.

The stimulus for fusion is a foreign particle that is too large for phagocytosis by one macrophage or has mechanisms to negate phagocytosis and killing mechanisms.

The giant cell exhibits multiple nuclei, often arranged in the periphery of the cell, and can measure up to 60 micrometres in diameter.

Foreign body giant cells are found at the core of granulomas produced by granulomatous inflammation.


Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.