Clinical indicator diseases for adult HIV infection

AIDS-defining conditions

other conditions where HIV testing should be offered

respiratory

• tuberculosis
• pneumocystis

• bacterial pneumonia
• aspergilosis

neurology

• cerebral toxoplasmosis
• primary cerebral lymphoma
• cryptococcal meningitis
• progressive multifactorial leucoencephalopathy

• aseptic meningitis/encephalitis
• cerebral abscess
• space occupying lesions of unknown origin
• Guillain -Barre syndrome
• transverse myelitis
• peripheral neuropathy
• dementia
• leucoencephalopathy

dermatology

• kaposi "s sarcoma

• severe or recalcitrant seborrhoeic dermatitis
• severe or recalcitrant psoriasis
• multidermatomal or recurrent herpes zoster

gastroenterology

• persistent cryptosporidiosis

• oral candidiasis
• oral hairy leukoplakia
• chronic diarrhoea of unknown cause
• weight loss of unknown cause
• salmonella, shigella or campylobacter
• hepatitis B & C infection

oncology

• non-Hodgkin "s lymphoma

• anal cancer or anal intraepithelial dysplasia
• lung cancer
• seminoma
• head and neck cancer
• Hodgkin "s lymphoma
• Castleman "s disease

gynaecology

• cervical cancer

• vaginal intraepithelial neoplasia
• cervical intraepithelial neoplasia Grade 2 or above

haematology

• any unexplained blood dyscrasia including:
  • thrombocytopenia
  • neutropenia
  • lymphopenia

ophthalmology

• cytomegalovirus retinitis

• infective retinal diseases including herpesviruses and toxoplasma
• any unexplained retinopathy

ENT

• lymphadenopathy of unknown cause
• chronic parotitis
• lymphoepithelial parotid cysts

other

• mononucleosis-like syndrome (primary HIV infection)
• pyrexia of unknown origin
• any lymphadenopathy of unknown cause
• any sexually transmitted infection