Diuretics
A diuretic is a compound which increases urine excretion.
The general principal of action is the inhibition of electrolyte reabsorption from the lumen of the nephron. Electrolytes which stay in the lumen increase the osmolarity and enhance water excretion.
Most diuretics partly work by natriuresis.
Reference
- Jackson EK. Drugs affecting renal excretory function. In, Brunton LL, Hilal-Dandan R, Knollman BC, eds. Goodman & Gilman’s the pharmacological basis of therapeutics. 13th ed. New York: McGraw-Hill, 2018, pp. 445-70.
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