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Aetiology

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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The most common cause of delayed puberty is constitutional delay of puberty which accounts for about 90% of cases. This is a diagnosis of exclusion.

Other causes include:

  • hypothalamic suppression e.g. systemic illness, anorexia nervosa
  • chromosomal abnormalities e.g. Klinefelter's, Turner's
  • gonodotrophin releasing hormone deficiency, pituitary lesion e.g. cranipharyngioma, gonadal failure, hypothyroidism, hyperprolactinoma

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