Increased destruction
Increased destruction may occur in:
- hereditary defects:
- haemoglobinopathies - sickle, thalassaemia
- membrane defects - spherocytosis
- enzyme problems - G6PD deficiency
- acquired problems
- haemolytic anaemias - immune and autoimmune
- burns
- artificial heart valves
- haemolytic uraemic syndrome
- snake venom
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