This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Antenatal screening methods

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

These include:

  • screening for fetal chromosome abnormalities
  • alpha fetoprotein screening for neural tube defects
  • screening tests based on alpha fetoprotein and other markers such as the triple test
  • screening for chromosomal or structural abnormalities using Ultrasound

Centres offer a routine Mid pregnancy anomaly ultrasound scan at 18+0-20+6 weeks (18 weeks - 20 weeks plus 6 days).


  • in the UK, maternal AFP is assessed in the context of other markers e .g. the quadruple test (hCG, AFP, uE3, inhibin A) to give a more accurate predictor of risk. However as many Trusts in England move to the offer of combined screening for Down's syndrome, AFP will no longer be measured and the screening test of choice for spina bifida and anencephaly will be the mid pregnancy ultrasound scan

Related pages

Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.


Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.