This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in


Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The investigation of choice is biopsy of the bone lesion, which reveals non-malignant proliferation of Langerhans cell histiocytes.

Under electron microscopy there are tennis racket-shaped Birbeck granules.

Radiology reveals a well-demarcated lytic lesion - the so called punched out lesion. A full skeletal survey may be indicated.

Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page