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Trichoepithelioma (multiple)

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Multiple trichoepithelioma is a rare epithelial tumour that attempts to differentiate into hair follicule cells. It is frequently dominantly-inherited and its gene has been mapped to chromosome 9p21.

After puberty, multiple skin-coloured nodules appear. Predominantly, these are on the face but they can appear on the scalp, neck and trunk. Histologically, there are multiple lacunae filled with keratin - horn cysts. There may be focal proliferations of basal cells. There may be failed attempts to form hair papillae and follicles.

Usually after a long duration, the trichoepithelioma may transform into an invasive basal cell epithelioma or carcinoma. Treatment is excision.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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