Interactions
For a comprehensive list consult the relevant appendix in the BNF.
Examples of drugs with a high potentiating effect for warfarin treatment include:
- cardiovascular - amiodarone, clofibrate, quinidine
- infections - metronidazole, co-trimoxazole, aminoglycosides
- gastrointestinal tract - cimetidine, antacids (magnesium salts), liquid parrafin and other laxatives
- endocrine - thyroxine, glucagon, anabolic steroids, danazol, corticosteroids, chlorpropamide, propylthiouracil, tolbutamide
- rheumatological - azapropazone, aspirin, salicylates, allopurinol
- central nervous system - chloral hydrate and related compounds, chlorpromazine, tricyclic antidepressants, dextropropoxyphene
- malignancy - tamoxifen
- nutrition - alcohol (dose dependent potentiator)
- other - disulfiram, interferon
Related pages
- Warfarin and alcohol
- Warfarin and antibiotics
- Amiodarone
- Fibrates
- Quinidine
- Metronidazole
- Co-trimoxazole
- Danazol
- Total T4
- Glucagon
- Aspirin
- Tamoxifen
- Disulfiram
- Interferon
- Hepatic microsomal enzyme inhibiting substances
- Antidepressants and warfarin
- Warfarin and combined oral contraceptive pill
- Proton pump inhibitors (PPIs) and warfarin
- warfarin and tramadol
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